Short Convergent Synthesis of the Mycolactone Core Through Lithiation-Borylation Homologations.
نویسندگان
چکیده
Using iterative lithiation-borylation homologations, the mycolactone toxin core has been synthesized in 13 steps and 17% overall yield. The rapid build-up of molecular complexity, high convergence and high stereoselectivity are noteworthy features of this synthesis.
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عنوان ژورنال:
- Chemistry
دوره 21 40 شماره
صفحات -
تاریخ انتشار 2015